An article published in the September issue of the openaccess journal PLoS Pathogens reports the findings of a team of scientists from the University of Michigan (UM). They have made a groundbreaking step toward what could become the first vaccine in the U.S. to prevent urinary tract infections. This will be the case if the [...]

UroToday.com Fragmentation of a prostate biopsy core can potentially impact the pathologic interpretation. A report in online version of the British Journal of Urology International by Dr. Jonathan Epsteins group at Johns Hopkins University assesses this variable.
A retrospective review was performed from 2007 to 2008 for prostate biopsy cases that contained prostate [...]

Urinary bladder cancer is more likely to be fatal in women than in men. With a maletofemale incidence ratio of approximately three to one, for women, the disease becomes fatal at a much earlier stage. The relative fiveyear survival rate for women is 72%(1) corresponding to a tenyear survival rate for men. One of [...]

The U.S. Food and Drug Administration said that it will require manufacturers of some immunosuppressant drugs used in kidney (renal) transplantation to update their labeling to reflect an increased risk of infections.
The required label changes affect the following immunosuppressant drugs used to help prevent rejection of transplanted organs
Rapamune (sirolimus) Sandimmune (cyclosporine) and cyclosporine [...]

Mayo Clinic cardiology researchers have found a peptide that helps preserve and improve kidney function during heart failure, without affecting blood pressure. Earlier variations of this peptide caused blood pressure to drop limiting the potential benefits to the kidneys. The findings appear in the current Proceedings of the National Academy of Sciences.
“Heart [...]

UroToday.com Nephronsparing surgery has become the wellaccepted method for treating patients with localized tumor disease of the kidney. Laparoscopic partial nephrectomy (LPN) has evolved such that it is considered equivalent to open partial nephrectomy for tumors 4 cm. They had 110 patients with Stage T1bT3N0M0 renal cell carcinoma treated with LRN (N=75) [...]

Dialysis is the artificial process of getting rid of waste (diffusion) and unwanted water (ultrafiltration) from the blood. This process is naturally done by our kidneys. Some people, however, may have failed or damaged kidneys which cannot carry out the function properly they may need dialysis. In other words, dialysis is the artificial replacement [...]

Today, GlaxoSmithKline (GSK) announced the results of a Phase III study demonstrating that pazopanib reduced the risk of tumour progression or death by 54% compared to placebo.1
Study findings demonstrated that the median time without tumour growth or death (progression free survival or PFS) in the pazopanib treated group was 9.2 months compared to 4.2 [...]

ZymoGenetics, Inc. (NASDAQZGEN) announced positive final results from a Phase 2 clinical trial in patients receiving 2nd or 3rd line therapy for advanced renal cell carcinoma with the combination of recombinant Interleukin 21 (IL21) and Nexavar® (sorafenib) tablets. The combination demonstrated considerable clinical benefit, with an overall response rate (as assessed by an independent review) [...]

The American Association of Kidney Patients (AAKP) is very disappointed with Wanda Sykes comedic comments regarding kidney failure and Rush Limbaugh at the White House Correspondent Dinner over the weekend. While Ms. Sykes comments were most likely made in a lighthearted manner, hundreds of thousands of kidney disease patients and their loved ones do [...]